Previous articleMahomes the rare quarterback with no weaknessNext articleAP Sportlight Digital AIM Web Support Phylloceuticals to Deliver Affordable Medicine to Underserved Areas Pinterest By Digital AIM Web Support – February 3, 2021 WhatsApp Pinterest Twitter WhatsApp TAGS Twitter DENVER, Feb. 3, 2021 /PRNewswire/ — Phylloceuticals, a privately-held, global technology company dedicated to providing medicine to underserved areas of the world, announced its formation today. The privately held company released details on their PhAAST™ platform, which uses plant-made pharmaceuticals to enable regions and countries to quickly ramp up production of much-needed biologics with public/private and private investment. PhAAST™, or Pharmaceuticals As A Service Technology, is a unique concept that uses a plant-made technology which offers rapid development of biopharmaceutical products at lower capital expense and operating cost. Drug development and manufacturing can happen fast (PhAAST™), enabling countries and regions to quickly develop reliable supply chains for needed biologics medicines. Rather than relying upon the traditional engineering and construction or CDMO models to deliver manufactured drugs, Phylloceuticals’ model helps nucleate teams to produce independently, with a proven production system and ongoing support from the Phylloceuticals team. Phyllo, which is a Greek work meaning ‘leaf,’ signifies the plant-made technology which fuels the PhAAST™ delivery. For more than three decades, the founding partners of Phylloceuticals have worked across the pharmaceutical industry. Their separate career paths have brought them together on a variety of award-winning projects. The strength and deep experience of the cross-functional team lies at the heart of the Phylloceuticals model. The company has a complete portfolio of skillsets, including drug development, regulatory strategy and enablement, full scale manufacturing and marketing support for company and product launch. PhAAST™ also includes groundbreaking data analytics, and top-level AI-enabled process control. This platform fosters continuous improvement and can be monitored from anywhere for a reproducible model that can be replicated across regions and markets underserved currently by large pharma. Phylloceuticals CEO Bill Brydges says: “In regions such as Vietnam, Africa, the MENA region and even Australia and Singapore, commonly prescribed biologics like rituximab for lymphoma and inflammatory diseases may currently be in short supply, or even unavailable to all but the wealthiest. COVID-19 highlighted supply chain difficulties for these regions. The need to rapidly ramp up and supply needed drugs for their own populations was the inspiration behind the formation of Phylloceuticals.” The rising demand for high-quality recombinant therapeutics has driven development of cell-based manufacturing systems for improved production yields. Yet cell-based systems require much higher capital investments and operating costs to finance. Protein therapies now treat a vast number of indications including cancer, diabetes, and inflammatory diseases, and provide a rapid response vaccine platform. Monoclonal antibodies represent the largest market segment at 40% of global market. Other categories include vaccines, antibody drug conjugates, enzyme replacement, diabetes treatments including recombinant insulin, interferons and blood factors. Phylloceutical CSO Barry Holtz, PhD says: “When you bring us an opportunity, feasibility data will be available for you very rapidly. Using our plant-made pharmaceutical (PMP) platform, scale-up is rapid and predictable from early stage process development. The upstream process is always the same and much more cost effective than traditional bioreactor based systems. We have designed a next-gen PMP system incorporating newer plant culture automation, real time AI analytics and the latest in downstream improvements for biologics manufacturing. The time to market is greatly reduced using these new systems and as a result of our years of experience in full-scale manufacturing.” “Prepare for some exciting news in the near future,” – Phylloceutical spokesperson Susan Stipa. The individuals on the Phylloceuticals team have been improving lives for forty years with a variety of skill sets, providing creative therapeutic solutions to difficult medical problems and solving complex challenges for biologics manufacturers. “The experience, expertise, and intellectual property that each of the Phylloceutical partners bring to the table is unsurpassed and highly complementary and their dedication to doing good, by helping underserved areas of the world gain access to the drugs they need, is truly admirable,” says Stipa. The news on the formation of Phylloceuticals was welcomed throughout the industry. “We believe the formation of such a novel new company to address the current weaknesses in the pharmaceutical supply chain couldn’t come at a better moment, says Dr. Sancha Salgueiro, CEO of Chart Bio in Denmark. “I know all of the partners personally, from their prior careers, and to see them collaboratively establish this new method of effectively delivering medicine to those with major unmet drug supply needs, is a tremendous step forward for our industry,” says Dr.Bernard Guay of BGC Pharma Consulting. Phylloceuticals will establish joint development agreements with investors, regions and clients. Other terms of the company formation were not disclosed. About Phylloceuticals Phylloceuticals is a global technology company dedicated to providing affordable medicine to underserved areas of the world. Founded in 2021, Phylloceuticals is rapidly building a reputation for solving complex technical challenges in the most demanding environments — and allowing needed drugs to be produced locally, with ongoing support from our team. Phylloceuticals uses a plant-made technology which offers lower overall investment and a much quicker response time for drug development. Drug development and manufacturing happen fast (PhAAST™), empowering underserved areas of the world to gain access to biologics medicines that other areas of the world take for granted. Phylloceuticals is not a CDMO. We are not a biologics or pharma company. Our mission is to nucleate, enable, and help construct companies in these traditionally underserved regions and underserved markets to manufacture biologics with our plant-made technology. We call it PhAAST™ – Pharmaceuticals as a Service Technology. About PhAAST™ PhAAST™ (Pharmaceuticals as a Service Technology) means: Lower cost facilities and operationsContinuous improvements in plant-made pharmaceutical manufacturing systemsRapid process and product development of new pharmaceutical candidatesContinuously optimized product vectors for an expanding product pipeline and increased production yield.Management and staff recruitment and trainingCentralized expert data management by automated quality control systems and data security through block chain technologyRegulatory support and clinical trial structure and managementDefinition of geographic regions for marketing products, with a special emphasis on bringing biologics manufacturing to underserved areasAssistance with obtaining capitalMarketing launch assistance for new companies For more information on Phylloceuticals, please visit http://phylloceuticals.com and connect with Phylloceuticals on LinkedIn. Media Contact: Susan Stipa, 484.883.8808, McDay|CGLife, mc-day.com Technical Contact: Barry Holtz, Ph.D., +1.281.794.1436, [email protected] View original content: http://www.prnewswire.com/news-releases/phylloceuticals-to-deliver-affordable-medicine-to-underserved-areas-301221246.html SOURCE Phylloceuticals Facebook Local NewsBusiness Facebook
Amateur Football Association put Oxford to the sword in pre-season friendly BLUES FOOTBALL Oxford 0 Amateur Football Association 4 An experimental Blues side, missing several key players, was well beaten by a fit and combative AFA side in the traditional curtain raiser to the new football season. New captain Arran Yentob saw his charges respond positively to a first-minute goal before spending the last hour on the rack, thanking goalkeeper Alexander Hill for a series of outstanding saves to keep the scoreline down. Ahead of the big BUSA kick-off against East Anglia, this was a useful workout for a team that comprised several players who will be looking to establish themselves in the OUFC setup. The match had barely kicked off when AFA striker Neil Hurst ran from what appeared to be an offside position to drill home the opener from eighteen yards. The Blues responded with some bright and confident approach play, and were almost rewarded when Dan Walbole burst clear, only to be denied by an excellent one-handed save. Both midfields closed space down well as the game tightened up, but the visitors were to change the course of proceedings in the twenty-seventh minute when Colin Hawkins beat Hill to the ball and finished from close range. The hosts’ confidence visibly drained, with the AFA’s Jack Costello starting to pull the strings for the London-based representative side, and the Hurst-Hawkins axis repeatedly causing havoc in a makeshift Oxford defence. The latter miscued a lob over Hill when well placed, and the Blues’ shot-stopper thwarted him with two point-blank saves in the space of fifteen seconds as half-time loomed. Hopes that the home side might effect a comeback were dashed by another early blow, as Hurst nodded home a right-wing corner only forty seconds after the restart. Hill then had to recover smartly to collect his own fumble from a Concannon drive, as his team-mates saw themselves repeatedly forced back by opponents whose extra fitness levels were becoming increasingly evident. Controversy again reared its head in the 57th minute as Hawkins’ looped header over Hill appeared to cross the line after bouncing down from the crossbar, but the referee’s assistant was well-placed to wave play on. The visitors’ striker was to claim his second ten minutes later, though, stabbing home after a corner was hooked back into the six-yard box. Osman Akkaya whipped a shot into the side netting for the Blues, but at the other end Costello saw a thirty-five yard effort narrowly miss the target and a driven free-kick fisted over by Hill. The home custodian completed his afternoon’s work with an acrobatic parry from Steve Hair’s hooked shot, and fine low saves from Gillard and Sonne.ARCHIVE: 1st Week MT2003
KRIS UGARIZZA/Herald photoFor its first seven games of the season, the Wisconsin men’s hockey team couldn’t find a victory. But the Badgers’ fortunes have turned as of late, as they are currently riding a five-game unbeaten streak following a tie and win against Minnesota-Duluth over the weekend.The three points have catapulted Mike Eaves’ team into third place in the WCHA standings, something he said the players have taken note of.“I know, just in the feedback of the kids, that now they look at the standing board when they walk by it, and they see where we are and where we’ve come from and what we’ve done here recently,” Eaves said in his press conference Monday. “There’s some good feelings. They’re excited, and they’re starting to believe in themselves. I think that’s something that when you come to practice now, we’re going to be able to hopefully continue on the path if we as coaches do our job and keep getting better and better.”UW and UMD tied 3-3 Friday in Duluth as Blake Geoffrion scored twice in the third period to give Wisconsin a short-lived 3-2 lead. The Badgers picked up the victory Saturday by a 4-1 margin — their fourth win in five games.“We’re really encouraged by the things we did on Saturday on the road in a tough building against a good opponent,” Eaves said. “The points are big because they’re conference play, and we just want to keep building on that.”Eaves’ team was able to weather the early storm of tough road games against ranked opponents. Wisconsin opened the year against Boston College, New Hampshire, Denver, Minnesota and North Dakota. It took the team’s seven freshmen awhile to get adjusted, Eaves said, but he believes they’re finally understanding the concept of WCHA hockey.“The beginning of the season, and especially in college athletics, you’ve got a whole bunch of new kids coming in that haven’t played together before. You’re trying to figure out after six practices what you have and where you’re going to go,” Eaves said. “With the schedule that we had, we just didn’t know what we had. We weren’t sure where we were. We had lots to work on. Now I think we’re just starting to get our feet underneath us.”“It’s like that old saying: you’ve got to crawl before you walk and walk before you can run. Well now we’re getting off our knees. We’re starting to walk, and hopefully soon here we’ll be running and even sprinting.”Home on the roadAdding to UW’s early adversity has been the fact that just four of its first 12 games have been played in the Kohl Center. The Badgers are again on the road this weekend when they travel to St. Cloud for a two-game series against the Huskies.Eaves and his team have had no choice but to adjust to life on the road.“You talk about the road trips, and I don’t know who made the schedule, but they certainly had a diabolical mind in their headset when they made this for us,” Eaves said. “I think it’s almost that you become comfortable playing on the road. You become comfortable adapting to hotels, the food, the rinks.”Wisconsin will again have to adjust to a difference in rink sizes. After playing at Minnesota Duluth’s DECC rink — 190 feet by 85 — the Badgers will be skating on a bigger sheet at St. Cloud State’s National Hockey Center — 200 by 100.“Now we go from a rink that was 185 [feet] in length to a rink that’s Olympic-sized,” Eaves said. “It will be a challenge for us, but going on those road trips early probably toughened us up. We talked about quite a bit that from toughness comes character. We’re developing a little character to win on the road.”No update on StreetSenior co-captain Ben Street suffered a leg injury in the second weekend of the season against Denver and hasn’t played since. He had surgery last week on the leg, but it is still uncertain whether he will return this year or seek a medical redshirt and attempt to play against next season.“That’s totally dependent — as I understand it — on his rehab. Everybody’s a little bit different,” Eaves said. “As soon as Ben can start rehabbing and doing the things that he needs to do, that will be the indicator of telling us what’s going to happen in the future.”
Sophomore driver Jacob Mercep’s 44 goals rank second on the team this season. (Josh Dunst | Daily Trojan)After a close 10-9 victory against the formerly top-ranked Stanford in the championship match of the Mountain Pacific Invitational last Sunday, No. 1 USC will take on two more top-10 opponents this weekend in No. 8 Long Beach State and No. 6 Pepperdine.The Trojans are coming off a strong weekend, not only securing a championship win but also sweeping the MPSF weekly honors. Freshman goalie Nic Porter was named Newcomer of the Week for the second time this season, while sophomore driver Jacob Mercep earned USC’s first Player of the Week honor of the season.Following the accomplishments of the past week, the team shifted its focus to prepare for Long Beach State and Pepperdine, drawing on strategies that have contributed to its prior successes.“We always have a specific preparation,” Mercep said. “[Head coach Jovan Vavic] does his job and the other coaches do their job very well. They break down the other team, and what they are trying to do, and when the game comes, we are ready for it and we know what’s coming.”The Men of Troy will face their first test of the weekend when they visit Long Beach State on Saturday. The two teams met at last weekend’s Mountain Pacific Invitational, where the Trojans bested the 49ers 14-8. Although USC has an all-time record of 70-15 against Long Beach, last year’s meeting between the two teams was quite close, with the Trojans narrowly defeating the 49ers in overtime at home.To come out on top against Long Beach, the Trojans will need to play well at both ends of the pool. A cohesive defensive effort will be necessary to counter the 49ers offense, led by redshirt junior attacker Austin Stewart, who boasts a team-high 33 goals this season. Capitalizing on offensive opportunities will also be important, as sophomore goalie Marwan Darwish has a .434 save percentage.After returning from Long Beach, the Trojans will face Pepperdine on Sunday. The Waves enter the weekend with an 11-8 overall record after a sixth-place finish in the Mountain Pacific Invitational. Pepperdine’s leading scorer is senior center Chris Dilworth, who has put up 43 goals so far this season. His performance has not gone unnoticed by the Trojan coaching staff, who have focused on defense in practice this week.“Defending fast breaks and opponents’ frontcourt offense is always our main emphasis, and I think we will only grow in our form during this season,” Mercep said of the team’s preparation.The Trojans plan to apply the lessons they learned in last weekend’s victory against Stanford, which handed the Trojans their only loss of the season, to this weekend’s matches against opponents of similar calibers.“Certainly we learned that we are tougher than we thought we were,” Mercep said of the Trojans’ tournament performance. “Whether things went good or bad, we showed character, and showed that we are really strong, collective and we stick together. We showed that we really can perform the way we set it up at the meetings, the way we agree upon doing.”Despite their No. 1 ranking, the Men of Troy continue to consider their potential for growth.“[Our play] can always be better,” Mercep said. “We are always trying to improve every day. We really strive towards excellence.”The weekend’s first opportunity for the Trojans will be Saturday at 1 p.m. at Long Beach State. The Trojans will host Sunday’s 1 p.m. match against Pepperdine at Uytengsu Aquatic Center.